The loss of the BH3-only Bcl-2 family member Bid delays T-cell leukemogenesis in Atm−/− mice

Multicellular organisms maintain genomic integrity and resist tumorigenesis through a tightly regulated DNA damage response (DDR) that prevents propagation of deleterious mutations either through DNA repair or programmed cell death. An impaired DDR leads to tumorigenesis that is accelerated when pro...

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Detalhes bibliográficos
Principais autores: Biswas, S, Shi, Q, Wernick, A, Aiello, A, Zinkel, S S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679453/
https://ncbi.nlm.nih.gov/pubmed/23470523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.16
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