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Circuitry and dynamics of human transcription factor regulatory networks

The combinatorial cross-regulation of hundreds of sequence-specific transcription factors defines a regulatory network that underlies cellular identity and function. Here we use genome-wide maps of in vivo DNaseI footprints to assemble an extensive core human regulatory network comprising connection...

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Autors principals: Neph, Shane, Stergachis, Andrew B., Reynolds, Alex, Sandstrom, Richard, Borenstein, Elhanan, Stamatoyannopoulos, John A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679407/
https://ncbi.nlm.nih.gov/pubmed/22959076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.04.040
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