Characterization and quantification of endogenous fatty acid nitroalkene metabolites in human urine

The oxidation and nitration of unsaturated fatty acids transforms cell membrane and lipoprotein constituents into mediators that regulate signal transduction. The formation of 9-NO(2)-octadeca-9,11-dienoic acid and 12-NO(2)-octadeca-9,11-dienoic acid stems from peroxynitrite- and myeloperoxidase-der...

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Autors principals: Salvatore, Sonia R., Vitturi, Dario A., Baker, Paul R. S., Bonacci, Gustavo, Koenitzer, Jeffrey R., Woodcock, Steven R., Freeman, Bruce A., Schopfer, Francisco J.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
Matèries:
Patient-Oriented and Epidemiological Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679401/
https://ncbi.nlm.nih.gov/pubmed/23620137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M037804
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