Detection and Quantification of Protein Adduction by Electrophilic Fatty Acids: Mitochondrial Generation of Fatty Acid Nitroalkene Derivatives

Nitroalkene fatty acid derivatives manifest a strong electrophilic nature, are clinically detectable and induce multiple transcriptionally-regulated anti-inflammatory responses. At present, the characterization and quantification of endogenous electrophilic lipids is compromised by their Michael add...

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Hauptverfasser: Schopfer, F.J., Batthyany, C., Baker, P.R.S., Bonacci, G., Cole, M.P., Rudolph, V., Groeger, A., Rudolph, T.K., Nadtochiy, S., Brookes, P.S., Freeman, B.A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144282/
https://ncbi.nlm.nih.gov/pubmed/19353781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.12.025
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