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Plasminogen activator inhibitor type 1 biosynthesis and mRNA level are increased by dexamethasone in human fibrosarcoma cells.

Dexamethasone increases type 1 plasminogen activator inhibitor (PAI-1) activity released from the human fibrosarcoma cell line HT-1080. We demonstrated that dexamethasone caused about 10-fold increases in the intracellular and extracellular levels of PAI-1 protein, as measured by an enzyme-linked im...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Andreasen, P A, Pyke, C, Riccio, A, Kristensen, P, Nielsen, L S, Lund, L R, Blasi, F, Danø, K
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1987
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367928/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3118190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.8.3021
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