Plasminogen activator inhibitor type 1 biosynthesis and mRNA level are increased by dexamethasone in human fibrosarcoma cells.

Dexamethasone increases type 1 plasminogen activator inhibitor (PAI-1) activity released from the human fibrosarcoma cell line HT-1080. We demonstrated that dexamethasone caused about 10-fold increases in the intracellular and extracellular levels of PAI-1 protein, as measured by an enzyme-linked im...

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Hauptverfasser: Andreasen, P A, Pyke, C, Riccio, A, Kristensen, P, Nielsen, L S, Lund, L R, Blasi, F, Danø, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC367928/
https://ncbi.nlm.nih.gov/pubmed/3118190
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