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Soluble Alpha-APP (sAPPalpha) Regulates CDK5 Expression and Activity in Neurons

A growing body of evidence suggests a role for soluble alpha-amyloid precursor protein (sAPPalpha) in pathomechanisms of Alzheimer disease (AD). This cleavage product of APP was identified to have neurotrophic properties. However, it remained enigmatic what proteins, targeted by sAPPalpha, might be...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hartl, Daniela, Klatt, Stephan, Roch, Manfred, Konthur, Zoltan, Klose, Joachim, Willnow, Thomas E., Rohe, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679172/
https://ncbi.nlm.nih.gov/pubmed/23776568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065920
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