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Secretory signal peptide modification for optimized antibody-fragment expression-secretion in Leishmania tarentolae

BACKGROUND: Secretory signal peptides (SPs) are well-known sequence motifs targeting proteins for translocation across the endoplasmic reticulum membrane. After passing through the secretory pathway, most proteins are secreted to the environment. Here, we describe the modification of an expression v...

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Detalhes bibliográficos
Main Authors: Klatt, Stephan, Konthur, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416730/
https://ncbi.nlm.nih.gov/pubmed/22830363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-97
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