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Secretory signal peptide modification for optimized antibody-fragment expression-secretion in Leishmania tarentolae

BACKGROUND: Secretory signal peptides (SPs) are well-known sequence motifs targeting proteins for translocation across the endoplasmic reticulum membrane. After passing through the secretory pathway, most proteins are secreted to the environment. Here, we describe the modification of an expression v...

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Hlavní autoři: Klatt, Stephan, Konthur, Zoltán
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416730/
https://ncbi.nlm.nih.gov/pubmed/22830363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-97
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