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Secretory signal peptide modification for optimized antibody-fragment expression-secretion in Leishmania tarentolae

BACKGROUND: Secretory signal peptides (SPs) are well-known sequence motifs targeting proteins for translocation across the endoplasmic reticulum membrane. After passing through the secretory pathway, most proteins are secreted to the environment. Here, we describe the modification of an expression v...

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Autors principals: Klatt, Stephan, Konthur, Zoltán
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416730/
https://ncbi.nlm.nih.gov/pubmed/22830363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-97
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