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Soluble Alpha-APP (sAPPalpha) Regulates CDK5 Expression and Activity in Neurons
A growing body of evidence suggests a role for soluble alpha-amyloid precursor protein (sAPPalpha) in pathomechanisms of Alzheimer disease (AD). This cleavage product of APP was identified to have neurotrophic properties. However, it remained enigmatic what proteins, targeted by sAPPalpha, might be...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679172/ https://ncbi.nlm.nih.gov/pubmed/23776568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065920 |
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