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Synthesis of Indole Derived Protease-Activated Receptor 4 Antagonists and Characterization in Human Platelets
Protease activated receptor-4 (PAR4) is one of the thrombin receptors on human platelets and is a potential target for the management of thrombotic disorders. We sought to develop potent, selective, and novel PAR4 antagonists to test the role of PAR4 in thrombosis and hemostasis. Development of an e...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679140/ https://ncbi.nlm.nih.gov/pubmed/23776495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065528 |
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