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Protease-Activated Receptor (PAR) 1 and PAR4 Differentially Regulate Factor V Expression from Human Platelets

With the recent interest of protease-activated receptors (PAR) 1 and PAR4 as possible targets for the treatment of thrombotic disorders, we compared the efficacy of protease-activated receptor (PAR)1 and PAR4 in the generation of procoagulant phenotypes on platelet membranes. PAR4-activating peptide...

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Bibliografiske detaljer
Main Authors: Duvernay, Matthew, Young, Summer, Gailani, David, Schoenecker, Jonathan, Hamm, Heidi
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608438/
https://ncbi.nlm.nih.gov/pubmed/23307185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.083477
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