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AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins, inhibits progression of human ovarian cancer

Ovarian carcinoma is the most deadly gynecological malignancy. Current chemotherapeutic drugs are only transiently effective and patients with advance disease often develop resistance despite significant initial responses. Mounting evidence suggests that anti-apoptotic proteins, including those of t...

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書目詳細資料
Main Authors: Brunckhorst, Melissa K., Lerner, Dimitry, Wang, Shaomeng, Yu, Qin
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679100/
https://ncbi.nlm.nih.gov/pubmed/22669575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20563
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