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AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins, inhibits progression of human ovarian cancer

Ovarian carcinoma is the most deadly gynecological malignancy. Current chemotherapeutic drugs are only transiently effective and patients with advance disease often develop resistance despite significant initial responses. Mounting evidence suggests that anti-apoptotic proteins, including those of t...

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Detalhes bibliográficos
Main Authors: Brunckhorst, Melissa K., Lerner, Dimitry, Wang, Shaomeng, Yu, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679100/
https://ncbi.nlm.nih.gov/pubmed/22669575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20563
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