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AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins, inhibits progression of human ovarian cancer

Ovarian carcinoma is the most deadly gynecological malignancy. Current chemotherapeutic drugs are only transiently effective and patients with advance disease often develop resistance despite significant initial responses. Mounting evidence suggests that anti-apoptotic proteins, including those of t...

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Détails bibliographiques
Auteurs principaux: Brunckhorst, Melissa K., Lerner, Dimitry, Wang, Shaomeng, Yu, Qin
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679100/
https://ncbi.nlm.nih.gov/pubmed/22669575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20563
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