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HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts

The nature of the cellular and molecular mechanisms for the transition of avascular cartilage replacement with bone during endochondral ossification remains poorly understood. One of the driving forces is hypoxia. As a master regulator of hypoxia, hypoxia-inducible factor-1α (HIF-1α) has been report...

詳細記述

保存先:
書誌詳細
主要な著者: Chen, Dafu, Li, Yang, Zhou, Zhiyu, Wu, Chengai, Xing, Yonggang, Zou, Xuenong, Tian, Wei, Zhang, Chi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679053/
https://ncbi.nlm.nih.gov/pubmed/23776575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065940
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