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HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts
The nature of the cellular and molecular mechanisms for the transition of avascular cartilage replacement with bone during endochondral ossification remains poorly understood. One of the driving forces is hypoxia. As a master regulator of hypoxia, hypoxia-inducible factor-1α (HIF-1α) has been report...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679053/ https://ncbi.nlm.nih.gov/pubmed/23776575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065940 |
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