HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts

The nature of the cellular and molecular mechanisms for the transition of avascular cartilage replacement with bone during endochondral ossification remains poorly understood. One of the driving forces is hypoxia. As a master regulator of hypoxia, hypoxia-inducible factor-1α (HIF-1α) has been report...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Dafu, Li, Yang, Zhou, Zhiyu, Wu, Chengai, Xing, Yonggang, Zou, Xuenong, Tian, Wei, Zhang, Chi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679053/
https://ncbi.nlm.nih.gov/pubmed/23776575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065940
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