HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts

The nature of the cellular and molecular mechanisms for the transition of avascular cartilage replacement with bone during endochondral ossification remains poorly understood. One of the driving forces is hypoxia. As a master regulator of hypoxia, hypoxia-inducible factor-1α (HIF-1α) has been report...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Chen, Dafu, Li, Yang, Zhou, Zhiyu, Wu, Chengai, Xing, Yonggang, Zou, Xuenong, Tian, Wei, Zhang, Chi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679053/
https://ncbi.nlm.nih.gov/pubmed/23776575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065940
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