HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts

The nature of the cellular and molecular mechanisms for the transition of avascular cartilage replacement with bone during endochondral ossification remains poorly understood. One of the driving forces is hypoxia. As a master regulator of hypoxia, hypoxia-inducible factor-1α (HIF-1α) has been report...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, Dafu, Li, Yang, Zhou, Zhiyu, Wu, Chengai, Xing, Yonggang, Zou, Xuenong, Tian, Wei, Zhang, Chi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679053/
https://ncbi.nlm.nih.gov/pubmed/23776575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065940
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