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Molecular Remodeling of Tip Links Underlies Mechanosensory Regeneration in Auditory Hair Cells

Sound detection by inner ear hair cells requires tip links that interconnect mechanosensory stereocilia and convey force to yet unidentified transduction channels. Current models postulate a static composition of the tip link, with protocadherin 15 (PCDH15) at the lower and cadherin 23 (CDH23) at th...

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Bibliografiska uppgifter
Huvudupphovsmän: Indzhykulian, Artur A., Stepanyan, Ruben, Nelina, Anastasiia, Spinelli, Kateri J., Ahmed, Zubair M., Belyantseva, Inna A., Friedman, Thomas B., Barr-Gillespie, Peter G., Frolenkov, Gregory I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679001/
https://ncbi.nlm.nih.gov/pubmed/23776407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001583
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