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Doxorubicin enhances nucleosome turnover around promoters
Doxorubicin is an anthracycline DNA intercalator that is among the most commonly used anti-cancer drugs [1]. Doxorubicin causes DNA double-strand breaks in rapidly dividing cells, although whether it also affects general chromatin properties is unknown. Here, we use a metabolic labeling strategy to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678987/ https://ncbi.nlm.nih.gov/pubmed/23602475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.03.043 |
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