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Doxorubicin, DNA torsion, and chromatin dynamics

Doxorubicin is one of the most important anti-cancer chemotherapeutic drugs, being widely used for the treatment of solid tumors and acute leukemias. The action of doxorubicin and other anthracycline drugs has been intensively investigated during the last several decades, but the mechanisms that hav...

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Main Authors: Yang, Fan, Teves, Sheila S., Kemp, Christopher J., Henikoff, Steven
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927826/
https://ncbi.nlm.nih.gov/pubmed/24361676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2013.12.002
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