Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathway

Activation of nuclear factor-kappa B (NF-κB) and related upstream signal transduction pathways have long been associated with the pathogenesis of a variety of inflammatory diseases and has recently been implicated in the onset of cancer. This report provides a synthetic and compound-based property s...

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Hlavní autoři: Hershberger, Paul M, Peddibhotla, Satyamaheshwar, Sessions, E Hampton, Divlianska, Daniela B, Correa, Ricardo G, Pinkerton, Anthony B, Reed, John C, Roth, Gregory P
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678512/
https://ncbi.nlm.nih.gov/pubmed/23766805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.103
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