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Viral population analysis and minority-variant detection using short read next-generation sequencing
RNA viruses within infected individuals exist as a population of evolutionary-related variants. Owing to evolutionary change affecting the constitution of this population, the frequency and/or occurrence of individual viral variants can show marked or subtle fluctuations. Since the development of ma...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678329/ https://ncbi.nlm.nih.gov/pubmed/23382427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0205 |
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