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Detection of somatic structural variants from short-read next-generation sequencing data

Somatic structural variants (SVs), which are variants that typically impact >50 nucleotides, play a significant role in cancer development and evolution but are notoriously more difficult to detect than small variants from short-read next-generation sequencing (NGS) data. This is due to a combina...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Gong, Tingting, Hayes, Vanessa M, Chan, Eva K F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138798/
https://ncbi.nlm.nih.gov/pubmed/32379294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbaa056
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