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Viral population analysis and minority-variant detection using short read next-generation sequencing

RNA viruses within infected individuals exist as a population of evolutionary-related variants. Owing to evolutionary change affecting the constitution of this population, the frequency and/or occurrence of individual viral variants can show marked or subtle fluctuations. Since the development of ma...

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Autores principales: Watson, Simon J., Welkers, Matthijs R. A., Depledge, Daniel P., Coulter, Eve, Breuer, Judith M., de Jong, Menno D., Kellam, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678329/
https://ncbi.nlm.nih.gov/pubmed/23382427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0205
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