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The Influence of Tim-3 Signaling on Central Nervous System Autoimmune Disease is Determined by the Effector Function of the Pathogenic T Cells
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system (CNS) mediated by self-reactive, myelin-specific T cells. Both CD4(+) and CD8(+) T cells play important roles in the pathogenesis of MS. MS is studied using experimental autoimmune encephalomyelitis (EAE)...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678277/ https://ncbi.nlm.nih.gov/pubmed/23562810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300083 |
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