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In Situ Tolerance within the Central Nervous System as a Mechanism for Preventing Autoimmunity

Multiple sclerosis (MS) is believed to be an autoimmune disease in which autoreactive T cells infiltrate the central nervous system (CNS). Animal models of MS have shown that CNS-specific T cells are present in the peripheral T cell repertoire of healthy mice and cause autoimmune disease only when t...

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Detalhes bibliográficos
Main Authors: Brabb, Thea, von Dassow, Peter, Ordonez, Nadia, Schnabel, Bryan, Duke, Blythe, Goverman, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193284/
https://ncbi.nlm.nih.gov/pubmed/10993917
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