Alternative inducers of the rat metallothionein I gene cause distinct changes in chromatin structure in the 5' region of the gene.
We examined the chromatin structure of the rat metallothionein I gene, both in uninduced cells and in cells induced by heavy metals or dexamethasone, using hypersensitivity to DNase I as an assay. The metallothionein I gene of the H4IIE rat hepatoma cell line, expressed at basal level, has a single...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1986
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3785203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.7.2576-2581.1986 |
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