Metal-dependent binding of a factor in vivo to the metal-responsive elements of the metallothionein 1 gene promoter.
Using the technique of genomic footprinting, we demonstrate cadmium-inducible protection from dimethyl sulfate (DMS) modification of guanine residues in vivo in five metal-responsive elements (MREs) in the promoter of the rat metallothionein 1 (MT-1) gene. We also identify a site of extreme DMS hype...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1987
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368011/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3683394/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.10.3574-3581.1987 |
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