Metal-dependent binding of a factor in vivo to the metal-responsive elements of the metallothionein 1 gene promoter.

Using the technique of genomic footprinting, we demonstrate cadmium-inducible protection from dimethyl sulfate (DMS) modification of guanine residues in vivo in five metal-responsive elements (MREs) in the promoter of the rat metallothionein 1 (MT-1) gene. We also identify a site of extreme DMS hype...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Andersen, R D, Taplitz, S J, Wong, S, Bristol, G, Larkin, B, Herschman, H R
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1987
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368011/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3683394/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.10.3574-3581.1987
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