Butyrate-induced changes in nuclease sensitivity of chromatin cannot be correlated with transcriptional activation.

We examined in the H4IIE rat hepatoma cell line the relationship between butyrate-induced changes in the nuclease sensitivity of chromatin and changes in transcriptional activity of specific genes. The butyrate-inducible metallothionein I (MT-I) gene underwent a dramatic increase in DNase I sensitiv...

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Bibliografske podrobnosti
Main Authors: Birren, B W, Taplitz, S J, Herschman, H R
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC368053/
https://ncbi.nlm.nih.gov/pubmed/3431545
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