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Thermostabilisation of the Serotonin Transporter in a Cocaine-Bound Conformation
Structure determination of mammalian integral membrane proteins is challenging due to their instability upon detergent solubilisation and purification. Recent successes in the structure determination of G-protein-coupled receptors (GPCRs) resulted from the development of GPCR-specific protein engine...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678023/ https://ncbi.nlm.nih.gov/pubmed/23706649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.03.025 |
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