Amplification of DNA sequences coding for the Na,K-ATPase alpha-subunit in ouabain-resistant C+ cells.
We have studied the mechanism of cellular resistance to cardiac glycosides in C+ cells. C+ cells were resistant to ouabain and overproduced plasma membrane-bound Na,K-ATPase relative to parental HeLa cells. Overexpression of Na,K-ATPase in C+ cells correlated with increased ATPase mRNA levels and am...
محفوظ في:
| الحاوية / القاعدة: | Mol Cell Biol |
|---|---|
| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Taylor & Francis
1986
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367801/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023935/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.7.2476-2481.1986 |
| الوسوم: |
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