The Elongation Complex Components BRD4 and MLLT3/AF9 Are Transcriptional Coactivators of Nuclear Retinoid Receptors

Nuclear all-trans retinoic acid receptors (RARs) initiate early transcriptional events which engage pluripotent cells to differentiate into specific lineages. RAR-controlled transactivation depends mostly on agonist-induced structural transitions in RAR C-terminus (AF-2), thus bridging coactivators...

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Autores principales: Flajollet, Sébastien, Rachez, Christophe, Ploton, Maheul, Schulz, Céline, Gallais, Rozenn, Métivier, Raphaël, Pawlak, Michal, Leray, Aymeric, Issulahi, Al Amine, Héliot, Laurent, Staels, Bart, Salbert, Gilles, Lefebvre, Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677938/
https://ncbi.nlm.nih.gov/pubmed/23762261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064880
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