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Discrete Roles for Peroxisome Proliferator-Activated Receptor γ and Retinoid X Receptor in Recruiting Nuclear Receptor Coactivators

Peroxisome proliferator-activated receptor γ (PPARγ) plays a major role in adipogenesis. PPARγ binds to DNA as a heterodimer with retinoid X receptor (RXR), and PPARγ-RXR can be activated by ligands specific for either receptor; the presence of both ligands can result in a cooperative effect on the...

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Detalhes bibliográficos
Main Authors: Yang, Wen, Rachez, Christophe, Freedman, Leonard P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86411/
https://ncbi.nlm.nih.gov/pubmed/11027271
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