Self-Oligomerization Is Essential for Enhanced Immunological Activities of Soluble Recombinant Calreticulin

We have recently reported that calreticulin (CRT), a luminal resident protein, can be found in the sera of patients with rheumatoid arthritis and also that recombinant CRT (rCRT) exhibits extraordinarily strong immunological activities. We herein further demonstrate that rCRT fragments 18–412 (rCRT/...

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Main Authors: Huang, Shang-Hui, Zhao, Li-Xiang, Hong, Chao, Duo, Cui-Cui, Guo, Bing-Nan, Zhang, Li-Juan, Gong, Zheng, Xiong, Si-Dong, Gong, Fang-Yuan, Gao, Xiao-Ming
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677884/
https://ncbi.nlm.nih.gov/pubmed/23762269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064951
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