Self-Oligomerization Is Essential for Enhanced Immunological Activities of Soluble Recombinant Calreticulin

We have recently reported that calreticulin (CRT), a luminal resident protein, can be found in the sera of patients with rheumatoid arthritis and also that recombinant CRT (rCRT) exhibits extraordinarily strong immunological activities. We herein further demonstrate that rCRT fragments 18–412 (rCRT/...

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Detalhes bibliográficos
Main Authors: Huang, Shang-Hui, Zhao, Li-Xiang, Hong, Chao, Duo, Cui-Cui, Guo, Bing-Nan, Zhang, Li-Juan, Gong, Zheng, Xiong, Si-Dong, Gong, Fang-Yuan, Gao, Xiao-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677884/
https://ncbi.nlm.nih.gov/pubmed/23762269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064951
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