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Regulatory Role of Glu546 in FMN-Heme Electron Transfer in Human Inducible NOS

Nitric oxide (NO) production by mammalian NO synthase (NOS) is believed to be regulated by the docking of the FMN domain in one subunit of the dimer onto the heme domain of the adjacent subunit. Glu546, a conserved charged surface residue of the FMN domain in human inducible NOS (iNOS), is proposed...

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Bibliografische gegevens
Hoofdauteurs: Li, Wenbing, Chen, Li, Lu, Changyuan, Elmore, Bradley O., Astashkin, Andrei V., Rousseau, Denis L., Yeh, Syun-Ru, Feng, Changjian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677850/
https://ncbi.nlm.nih.gov/pubmed/23570607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic3020892
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