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Endothelin-Converting Enzymes and Related Metalloproteases in Alzheimer’s Disease

The efficient clearance of amyloid β (Aβ) is essential to modulate levels of the peptide in the brain and to prevent it from accumulating in senile plaques, a hallmark of AD pathology. We and others have shown that failure in Aβ catabolism can produce elevations in Aβ concentration similar to those...

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Detalhes bibliográficos
Main Authors: Pacheco-Quinto, Javier, Herdt, Aimee, Eckman, Christopher B., Eckman, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677825/
https://ncbi.nlm.nih.gov/pubmed/22903130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-129043
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