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Augmentation of therapeutic responses in melanoma by inhibition of IRAK-1,-4

Toll-like receptors (TLR) are expressed by a variety of cancers, including melanoma, but their functional contributions in cancer cells are uncertain. To approach this question, we evaluated the effects of stimulating or inhibiting the TLR/IL-1 receptor-associated kinases IRAK-1 and IRAK-4 in melano...

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Detalhes bibliográficos
Main Authors: Srivastava, Ratika, Geng, Degui, Liu, Yingjia, Zheng, Liqin, Li, Zhaoyang, Joseph, Mary Ann, McKenna, Colleen, Bansal, Navneeta, Ochoa, Augusto, Davila, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677596/
https://ncbi.nlm.nih.gov/pubmed/23041547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0337
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