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Inhibition of IRAK1/4 sensitizes T cell acute lymphoblastic leukemia to chemotherapies
Signaling via the MyD88/IRAK pathway in T cells is indispensable for cell survival; however, it is not known whether this pathway functions in the progression of T acute lymphoblastic leukemia (T-ALL). Here, we determined that compared with thymic and peripheral T cells, T-ALL cells from patients ha...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362243/ https://ncbi.nlm.nih.gov/pubmed/25642772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75821 |
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