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Thiolates Chemically Induce Redox Activation of BTZ043 and Related Potent Nitro Aromatic Anti-Tuberculosis Agents

The development of multidrug resistant (MDR) and extensively drug resistant (XDR) forms of tuberculosis (TB) has stimulated research efforts globally to expand the new drug pipeline. Nitro aromatic compounds, including 1, 3-Benzothiazin-4-ones (BTZs) and related agents, are a promising new class for...

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Hlavní autoři: Tiwari, Rohit, Moraski, Garrett C., Krchňák, Viktor, Miller, Patricia A., Colon-Martinez, Mariangelli, Herrero, Eliza, Oliver, Allen G., Miller, Marvin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677520/
https://ncbi.nlm.nih.gov/pubmed/23402278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311058q
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