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Thiolates Chemically Induce Redox Activation of BTZ043 and Related Potent Nitro Aromatic Anti-Tuberculosis Agents

The development of multidrug resistant (MDR) and extensively drug resistant (XDR) forms of tuberculosis (TB) has stimulated research efforts globally to expand the new drug pipeline. Nitro aromatic compounds, including 1, 3-Benzothiazin-4-ones (BTZs) and related agents, are a promising new class for...

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Autors principals: Tiwari, Rohit, Moraski, Garrett C., Krchňák, Viktor, Miller, Patricia A., Colon-Martinez, Mariangelli, Herrero, Eliza, Oliver, Allen G., Miller, Marvin J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677520/
https://ncbi.nlm.nih.gov/pubmed/23402278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311058q
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