Thiolates Chemically Induce Redox Activation of BTZ043 and Related Potent Nitro Aromatic Anti-Tuberculosis Agents

The development of multidrug resistant (MDR) and extensively drug resistant (XDR) forms of tuberculosis (TB) has stimulated research efforts globally to expand the new drug pipeline. Nitro aromatic compounds, including 1, 3-Benzothiazin-4-ones (BTZs) and related agents, are a promising new class for...

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Main Authors: Tiwari, Rohit, Moraski, Garrett C., Krchňák, Viktor, Miller, Patricia A., Colon-Martinez, Mariangelli, Herrero, Eliza, Oliver, Allen G., Miller, Marvin J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677520/
https://ncbi.nlm.nih.gov/pubmed/23402278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311058q
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