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Interplay of physics and evolution in the likely origin of protein biochemical function
The intrinsic ability of protein structures to exhibit the geometric and sequence properties required for ligand binding without evolutionary selection is shown by the coincidence of the properties of pockets in native, single domain proteins with those in computationally generated, compact homopoly...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677488/ https://ncbi.nlm.nih.gov/pubmed/23690621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300011110 |
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