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Interplay of physics and evolution in the likely origin of protein biochemical function

The intrinsic ability of protein structures to exhibit the geometric and sequence properties required for ligand binding without evolutionary selection is shown by the coincidence of the properties of pockets in native, single domain proteins with those in computationally generated, compact homopoly...

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Sonraí Bibleagrafaíochta
Main Authors: Skolnick, Jeffrey, Gao, Mu
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677488/
https://ncbi.nlm.nih.gov/pubmed/23690621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300011110
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