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Interplay of physics and evolution in the likely origin of protein biochemical function
The intrinsic ability of protein structures to exhibit the geometric and sequence properties required for ligand binding without evolutionary selection is shown by the coincidence of the properties of pockets in native, single domain proteins with those in computationally generated, compact homopoly...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677488/ https://ncbi.nlm.nih.gov/pubmed/23690621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300011110 |
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