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Interplay of physics and evolution in the likely origin of protein biochemical function

The intrinsic ability of protein structures to exhibit the geometric and sequence properties required for ligand binding without evolutionary selection is shown by the coincidence of the properties of pockets in native, single domain proteins with those in computationally generated, compact homopoly...

詳細記述

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書誌詳細
主要な著者: Skolnick, Jeffrey, Gao, Mu
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677488/
https://ncbi.nlm.nih.gov/pubmed/23690621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300011110
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