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Microtubule dynamic instability: A new model with coupled GTP hydrolysis and multistep catastrophe

A key question in understanding microtubule dynamics is how GTP hydrolysis leads to catastrophe, the switch from slow growth to rapid shrinkage. We first provide a review of the experimental and modeling literature, and then present a new model of microtubule dynamics. We demonstrate that vectorial,...

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Autors principals: Bowne-Anderson, Hugo, Zanic, Marija, Kauer, Monika, Howard, Jonathon
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677417/
https://ncbi.nlm.nih.gov/pubmed/23532586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200131
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