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Microtubule dynamic instability: A new model with coupled GTP hydrolysis and multistep catastrophe
A key question in understanding microtubule dynamics is how GTP hydrolysis leads to catastrophe, the switch from slow growth to rapid shrinkage. We first provide a review of the experimental and modeling literature, and then present a new model of microtubule dynamics. We demonstrate that vectorial,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
WILEY-VCH Verlag
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677417/ https://ncbi.nlm.nih.gov/pubmed/23532586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200131 |
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