Gene Silencing via RNAi and siRNA Quantification in Tumor Tissue Using MEND, a Liposomal siRNA Delivery System

Small interfering RNA (siRNA) would be predicted to function as a cancer drug, but an efficient siRNA delivery system is required for clinical development. To address this issue, we developed a liposomal siRNA carrier, a multifunctional envelope-type nanodevice (MEND). We previously reported that a...

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Bibliografiske detaljer
Main Authors: Sakurai, Yu, Hatakeyama, Hiroto, Sato, Yusuke, Hyodo, Mamoru, Akita, Hidetaka, Harashima, Hideyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677313/
https://ncbi.nlm.nih.gov/pubmed/23568259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.57
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