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Class Switch Recombination Efficiency and Junction Microhomology Patterns in Msh2-, Mlh1-, and Exo1-Deficient Mice Depend on the Presence of μ Switch Region Tandem Repeats()
The Msh2 mismatch repair (MMR) protein is critical for class switch recombination (CSR) events that occur in mice that lack the Sμ tandem repeat (SμTR) region (SμTR(−/−) mice). The pattern of microhomology among switch junction sites in Msh2-deficient mice is also dependent on the presence or absenc...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677205/ https://ncbi.nlm.nih.gov/pubmed/19553545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900135 |
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